1vft: Difference between revisions

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[[Image:1vft.gif|left|200px]]<br /><applet load="1vft" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1vft.gif|left|200px]]
caption="1vft, resolution 2.30&Aring;" />
 
'''Crystal structure of L-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae'''<br />
{{Structure
|PDB= 1vft |SIZE=350|CAPTION= <scene name='initialview01'>1vft</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=DCS:D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE'>DCS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alanine_racemase Alanine racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.1 5.1.1.1]
|GENE= alr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1914 Streptomyces lavendulae])
}}
 
'''Crystal structure of L-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1VFT is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_lavendulae Streptomyces lavendulae] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=DCS:'>DCS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alanine_racemase Alanine racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.1 5.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VFT OCA].  
1VFT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_lavendulae Streptomyces lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VFT OCA].  


==Reference==
==Reference==
Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product., Noda M, Matoba Y, Kumagai T, Sugiyama M, J Biol Chem. 2004 Oct 29;279(44):46153-61. Epub 2004 Aug 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15302886 15302886]
Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product., Noda M, Matoba Y, Kumagai T, Sugiyama M, J Biol Chem. 2004 Oct 29;279(44):46153-61. Epub 2004 Aug 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15302886 15302886]
[[Category: Alanine racemase]]
[[Category: Alanine racemase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: tim-barrel]]
[[Category: tim-barrel]]


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