2kzg: Difference between revisions
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{{STRUCTURE_2kzg| PDB=2kzg | SCENE= }} | {{STRUCTURE_2kzg| PDB=2kzg | SCENE= }} | ||
===A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution=== | ===A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution=== | ||
{{ABSTRACT_PUBMED_20829478}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN]] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2kzg]] is a 1 chain structure | [[2kzg]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KZG OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020829478</ref><references group="xtra"/> | <ref group="xtra">PMID:020829478</ref><references group="xtra"/><references/> | ||
[[Category: Banachewicz, W.]] | [[Category: Banachewicz, W.]] | ||
[[Category: Fersht, A R.]] | [[Category: Fersht, A R.]] | ||
Revision as of 10:51, 1 January 2014
A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution
Template:ABSTRACT PUBMED 20829478
Function
[PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.[1]
About this Structure
2kzg is a 1 chain structure. Full experimental information is available from OCA.
Reference
- Korzhnev DM, Religa TL, Banachewicz W, Fersht AR, Kay LE. A transient and low-populated protein-folding intermediate at atomic resolution. Science. 2010 Sep 10;329(5997):1312-6. PMID:20829478 doi:10.1126/science.1191723
- ↑ Bai SW, Herrera-Abreu MT, Rohn JL, Racine V, Tajadura V, Suryavanshi N, Bechtel S, Wiemann S, Baum B, Ridley AJ. Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol. 2011 Aug 11;9:54. doi: 10.1186/1741-7007-9-54. PMID:21834987 doi:10.1186/1741-7007-9-54
