1vwh: Difference between revisions

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[[Image:1vwh.gif|left|200px]]<br /><applet load="1vwh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1vwh.gif|left|200px]]
caption="1vwh, resolution 1.48&Aring;" />
 
'''STREPTAVIDIN COMPLEXED WITH THE HEAD-TO-TAIL DISULFIDE-BONDED PEPTIDE DIMER OF CYCLO-AC-[CHPQGPPC]-NH2, PH 3.5'''<br />
{{Structure
|PDB= 1vwh |SIZE=350|CAPTION= <scene name='initialview01'>1vwh</scene>, resolution 1.48&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY=
|GENE=
}}
 
'''STREPTAVIDIN COMPLEXED WITH THE HEAD-TO-TAIL DISULFIDE-BONDED PEPTIDE DIMER OF CYCLO-AC-[CHPQGPPC]-NH2, PH 3.5'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1VWH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii] with <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VWH OCA].  
1VWH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VWH OCA].  


==Reference==
==Reference==
In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0., Katz BA, Cass RT, J Biol Chem. 1997 May 16;272(20):13220-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9148939 9148939]
In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0., Katz BA, Cass RT, J Biol Chem. 1997 May 16;272(20):13220-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9148939 9148939]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
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[[Category: cyclic peptide discovered by phage display]]
[[Category: cyclic peptide discovered by phage display]]


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