1w0e: Difference between revisions

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[[Image:1w0e.gif|left|200px]]~~<br /><applet load~~="1w0e~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1w0e.gif|left|200px]]

~~caption="~~1w0e, resolution 2.8Å" />

'''CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4'''~~<br />~~

{{Structure

|PDB= 1w0e |SIZE=350|CAPTION= <scene name='initialview01'>1w0e</scene>, resolution 2.8Å

|SITE= <scene name='pdbsite=AC1:Hem+Binding+Site+For+Chain+A'>AC1</scene>

|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>

|ACTIVITY=

|GENE=

}}

'''CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4'''

==Overview==

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==About this Structure==

1W0E is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. The following page contains interesting information on the relation of 1W0E with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb82_1.html Cytochrome p450]]~~. Known structural/functional Site: <scene name='pdbsite=AC1:Hem+Binding+Site+For+Chain+A'>AC1</scene>~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W0E OCA].

1W0E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1W0E with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb82_1.html Cytochrome p450]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W0E OCA].

==Reference==

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone., Williams PA, Cosme J, Vinkovic DM, Ward A, Angove HC, Day PJ, Vonrhein C, Tickle IJ, Jhoti H, Science. 2004 Jul 30;305(5684):683-6. Epub 2004 Jul 15. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15256616 15256616]

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone., Williams PA, Cosme J, Vinkovic DM, Ward A, Angove HC, Day PJ, Vonrhein C, Tickle IJ, Jhoti H, Science. 2004 Jul 30;305(5684):683-6. Epub 2004 Jul 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15256616 15256616]

[[Category: Cytochrome p450]]

[[Category: Homo sapiens]]

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[[Category: oxidoreductase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 15~~:39:12 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:50:24 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1w0e.gif|left|200px]]<br /><applet load="1w0e" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1w0e.gif|left|200px]]
-caption="1w0e, resolution 2.8&Aring;" />
-'''CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4'''<br />
+ {{Structure
+|PDB= 1w0e |SIZE=350|CAPTION= <scene name='initialview01'>1w0e</scene>, resolution 2.8&Aring;
+|SITE= <scene name='pdbsite=AC1:Hem+Binding+Site+For+Chain+A'>AC1</scene>
+|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-W0E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. The following page contains interesting information on the relation of 1W0E with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb82_1.html Cytochrome p450]]. Known structural/functional Site: <scene name='pdbsite=AC1:Hem+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W0E OCA].
+W0E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1W0E with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb82_1.html Cytochrome p450]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W0E OCA].
 ==Reference==
-Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone., Williams PA, Cosme J, Vinkovic DM, Ward A, Angove HC, Day PJ, Vonrhein C, Tickle IJ, Jhoti H, Science. 2004 Jul 30;305(5684):683-6. Epub 2004 Jul 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15256616 15256616]
+Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone., Williams PA, Cosme J, Vinkovic DM, Ward A, Angove HC, Day PJ, Vonrhein C, Tickle IJ, Jhoti H, Science. 2004 Jul 30;305(5684):683-6. Epub 2004 Jul 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15256616 15256616]
 [[Category: Cytochrome p450]]
 [[Category: Homo sapiens]]
@@ Line 30: / Line 39: @@
 [[Category: oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:39:12 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:50:24 2008''