2k1q: Difference between revisions

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Revision as of 11:22, 7 January 2013

File:2k1q.png

Template:STRUCTURE 2k1q

NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor

Template:ABSTRACT PUBMED 19061898

About this Structure

2k1q is a 2 chain structure with sequence from Hepatitis c virus. Full experimental information is available from OCA.

Reference

  1. Gallo M, Pennestri M, Bottomley MJ, Barbato G, Eliseo T, Paci M, Narjes F, De Francesco R, Summa V, Koch U, Bazzo R, Cicero DO. Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor. J Mol Biol. 2009 Jan 30;385(4):1142-55. Epub 2008 Nov 24. PMID:19061898 doi:10.1016/j.jmb.2008.11.017

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