1w6k: Difference between revisions

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[[Image:1w6k.gif|left|200px]]~~<br /><applet load~~="1w6k~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1w6k.gif|left|200px]]

~~caption="~~1w6k, resolution 2.1Å" />

'''STRUCTURE OF HUMAN OSC IN COMPLEX WITH LANOSTEROL'''~~<br />~~

{{Structure

|PDB= 1w6k |SIZE=350|CAPTION= <scene name='initialview01'>1w6k</scene>, resolution 2.1Å

|SITE= <scene name='pdbsite=AC1:Lan+Binding+Site+For+Chain+A'>AC1</scene>

|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene> and <scene name='pdbligand=LAN:LANOSTEROL'>LAN</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Lanosterol_synthase Lanosterol synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.7 5.4.99.7]

|GENE=

}}

'''STRUCTURE OF HUMAN OSC IN COMPLEX WITH LANOSTEROL'''

==Overview==

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==About this Structure==

1W6K is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BOG:'>BOG</scene> and <scene name='pdbligand=LAN:'>LAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lanosterol_synthase Lanosterol synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.7 5.4.99.7] Known structural/functional Site: <scene name='pdbsite=AC1:Lan+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6K OCA].

1W6K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6K OCA].

==Reference==

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase., Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A, Nature. 2004 Nov 4;432(7013):118-22. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15525992 15525992]

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase., Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A, Nature. 2004 Nov 4;432(7013):118-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15525992 15525992]

[[Category: Homo sapiens]]

[[Category: Lanosterol synthase]]

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[[Category: steroid biosynthesis]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:52:49 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1w6k.gif|left|200px]]<br /><applet load="1w6k" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1w6k.gif|left|200px]]
-caption="1w6k, resolution 2.1&Aring;" />
-'''STRUCTURE OF HUMAN OSC IN COMPLEX WITH LANOSTEROL'''<br />
+ {{Structure
+|PDB= 1w6k |SIZE=350|CAPTION= <scene name='initialview01'>1w6k</scene>, resolution 2.1&Aring;
+|SITE= <scene name='pdbsite=AC1:Lan+Binding+Site+For+Chain+A'>AC1</scene>
+|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene> and <scene name='pdbligand=LAN:LANOSTEROL'>LAN</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Lanosterol_synthase Lanosterol synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.7 5.4.99.7]
+|GENE=
+}}
+'''STRUCTURE OF HUMAN OSC IN COMPLEX WITH LANOSTEROL'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-W6K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BOG:'>BOG</scene> and <scene name='pdbligand=LAN:'>LAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lanosterol_synthase Lanosterol synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.7 5.4.99.7] Known structural/functional Site: <scene name='pdbsite=AC1:Lan+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6K OCA].
+W6K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6K OCA].
 ==Reference==
-Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase., Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A, Nature. 2004 Nov 4;432(7013):118-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15525992 15525992]
+Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase., Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A, Nature. 2004 Nov 4;432(7013):118-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15525992 15525992]
 [[Category: Homo sapiens]]
 [[Category: Lanosterol synthase]]
@@ Line 35: / Line 44: @@
 [[Category: steroid biosynthesis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:41:04 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:52:49 2008''