2hac: Difference between revisions
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{{STRUCTURE_2hac| PDB=2hac | SCENE= }} | {{STRUCTURE_2hac| PDB=2hac | SCENE= }} | ||
===Structure of Zeta-Zeta Transmembrane Dimer=== | |||
{{ABSTRACT_PUBMED_17055436}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CD3Z_HUMAN CD3Z_HUMAN]] Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:[http://omim.org/entry/610163 610163]]. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.<ref>PMID:16672702</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CD3Z_HUMAN CD3Z_HUMAN]] Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:017055436</ref><references group="xtra"/> | <ref group="xtra">PMID:017055436</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Call, M E.]] | [[Category: Call, M E.]] | ||
