1wb0: Difference between revisions

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[[Image:1wb0.gif|left|200px]]<br /><applet load="1wb0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wb0.gif|left|200px]]
caption="1wb0, resolution 1.65&Aring;" />
 
'''SPECIFICITY AND AFFINITY OF NATURAL PRODUCT CYCLOPENTAPEPTIDE INHIBITOR ARGIFIN AGAINST HUMAN CHITINASE'''<br />
{{Structure
|PDB= 1wb0 |SIZE=350|CAPTION= <scene name='initialview01'>1wb0</scene>, resolution 1.65&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=RAG:ARGIFIN'>RAG</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14]
|GENE=
}}
 
'''SPECIFICITY AND AFFINITY OF NATURAL PRODUCT CYCLOPENTAPEPTIDE INHIBITOR ARGIFIN AGAINST HUMAN CHITINASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WB0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=RAG:'>RAG</scene>, <scene name='pdbligand=IPA:'>IPA</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WB0 OCA].  
1WB0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WB0 OCA].  


==Reference==
==Reference==
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases., Rao FV, Houston DR, Boot RG, Aerts JM, Hodkinson M, Adams DJ, Shiomi K, Omura S, van Aalten DM, Chem Biol. 2005 Jan;12(1):65-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15664516 15664516]
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases., Rao FV, Houston DR, Boot RG, Aerts JM, Hodkinson M, Adams DJ, Shiomi K, Omura S, van Aalten DM, Chem Biol. 2005 Jan;12(1):65-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15664516 15664516]
[[Category: Chitinase]]
[[Category: Chitinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: chitin degradation]]
[[Category: chitin degradation]]
[[Category: chitin-binding]]
[[Category: chitin-binding]]
[[Category: chitinase inhibitors]]
[[Category: chitinase inhibitor]]
[[Category: cyclopentapeptide inhibitors]]
[[Category: cyclopentapeptide inhibitor]]
[[Category: glycosidase]]
[[Category: glycosidase]]
[[Category: human chitinase]]
[[Category: human chitinase]]
[[Category: hydrolase]]
[[Category: hydrolase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:42:22 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:54:36 2008''