1wbo: Difference between revisions

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[[Image:1wbo.gif|left|200px]]<br /><applet load="1wbo" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wbo.gif|left|200px]]
caption="1wbo, resolution 2.16&Aring;" />
 
'''FRAGMENT BASED P38 INHIBITORS'''<br />
{{Structure
|PDB= 1wbo |SIZE=350|CAPTION= <scene name='initialview01'>1wbo</scene>, resolution 2.16&Aring;
|SITE= <scene name='pdbsite=AC1:2ch+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=2CH:2-CHLOROPHENOL'>2CH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37]
|GENE=
}}
 
'''FRAGMENT BASED P38 INHIBITORS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WBO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=2CH:'>2CH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37] Known structural/functional Site: <scene name='pdbsite=AC1:2ch+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBO OCA].  
1WBO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBO OCA].  


==Reference==
==Reference==
Fragment-based lead discovery using X-ray crystallography., Hartshorn MJ, Murray CW, Cleasby A, Frederickson M, Tickle IJ, Jhoti H, J Med Chem. 2005 Jan 27;48(2):403-13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15658854 15658854]
Fragment-based lead discovery using X-ray crystallography., Hartshorn MJ, Murray CW, Cleasby A, Frederickson M, Tickle IJ, Jhoti H, J Med Chem. 2005 Jan 27;48(2):403-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15658854 15658854]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


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