2g6q: Difference between revisions
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m Protected "2g6q" [edit=sysop:move=sysop] |
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{{STRUCTURE_2g6q| PDB=2g6q | SCENE= }} | {{STRUCTURE_2g6q| PDB=2g6q | SCENE= }} | ||
===Crystal structure of ING2 PHD finger in complex with H3K4Me3 peptide=== | |||
{{ABSTRACT_PUBMED_16728977}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/ING2_MOUSE ING2_MOUSE]] Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs) (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016728977</ref><references group="xtra"/> | <ref group="xtra">PMID:016728977</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Kutateladze, T G.]] | [[Category: Kutateladze, T G.]] | ||
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[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Gene regulation]] | [[Category: Gene regulation]] | ||
[[Category: Phd finger]] | |||
[[Category: Protein-peptide complex]] | [[Category: Protein-peptide complex]] | ||
