1we2: Difference between revisions

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[[Image:1we2.gif|left|200px]]<br /><applet load="1we2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1we2.gif|left|200px]]
caption="1we2, resolution 2.30&Aring;" />
 
'''Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with MGADP and shikimic acid'''<br />
{{Structure
|PDB= 1we2 |SIZE=350|CAPTION= <scene name='initialview01'>1we2</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=DHK:3-DEHYDROSHIKIMATE'>DHK</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Shikimate_kinase Shikimate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.71 2.7.1.71]
|GENE= AROK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with MGADP and shikimic acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WE2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=DHK:'>DHK</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Shikimate_kinase Shikimate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.71 2.7.1.71] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WE2 OCA].  
1WE2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WE2 OCA].  


==Reference==
==Reference==
Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid., Pereira JH, de Oliveira JS, Canduri F, Dias MV, Palma MS, Basso LA, Santos DS, de Azevedo WF Jr, Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 2):2310-9. Epub, 2004 Nov 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15583379 15583379]
Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid., Pereira JH, de Oliveira JS, Canduri F, Dias MV, Palma MS, Basso LA, Santos DS, de Azevedo WF Jr, Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 2):2310-9. Epub, 2004 Nov 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15583379 15583379]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Shikimate kinase]]
[[Category: Shikimate kinase]]
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[[Category: x-ray crystallography]]
[[Category: x-ray crystallography]]


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