2g1z: Difference between revisions
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[[ | ==X-ray structure of the oligonucleotide sequence d(AAATTT)== | ||
<StructureSection load='2g1z' size='340' side='right' caption='[[2g1z]], [[Resolution|resolution]] 3.11Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2g1z]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G1Z FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g1z RCSB], [http://www.ebi.ac.uk/pdbsum/2g1z PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
We describe the packing features of the oligonucleotide duplex d(AAATTT)2, as determined by X-ray diffraction. There is little information on sequences that only contain A and T bases. The present structure confirms that these sequences tend to pack as a helical arrangement of stacked oligonucleotides in a B conformation with Watson-Crick hydrogen bonding. Our results demonstrate that the virtual TA base step between stacked duplexes has a negative twist that improves base stacking. This observation is consistent with the low stability of TA base steps in B-form DNA. | |||
Packing features of the all-AT oligonucleotide d(AAATTT).,Valls N, Santaolalla A, Campos JL, Subirana JA J Biomol Struct Dyn. 2007 Jun;24(6):547-52. PMID:17508776<ref>PMID:17508776</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
== | |||
< | |||
[[Category: Campos, J L.]] | [[Category: Campos, J L.]] | ||
[[Category: Santaolalla, A.]] | [[Category: Santaolalla, A.]] | ||