1wug: Difference between revisions

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[[Image:1wug.gif|left|200px]]<br />~~<applet load~~=~~"1wug" size~~=~~"350" color~~=~~"white" frame~~=~~"true" align~~=~~"right" spinBox~~=~~"true"~~

[[Image:1wug.gif|left|200px]]

~~caption~~=~~"1wug"~~ />

'''complex structure of PCAF bromodomain with small chemical ligand NP1'''~~<br />~~

{{Structure

|PDB= 1wug |SIZE=350|CAPTION= <scene name='initialview01'>1wug</scene>

|SITE=

|LIGAND= <scene name='pdbligand=NP1:N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE'>NP1</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48]

|GENE= PCAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])

}}

'''complex structure of PCAF bromodomain with small chemical ligand NP1'''

==Overview==

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==About this Structure==

1WUG is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] ~~with <scene name='pdbligand=NP1:'>NP1</scene> as [http://en.wikipedia~~.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUG OCA].

1WUG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUG OCA].

==Reference==

Selective small molecules blocking HIV-1 Tat and coactivator PCAF association., Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C, Wang Z, Zhou MM, J Am Chem Soc. 2005 Mar 2;127(8):2376-7. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15724976 15724976]

Selective small molecules blocking HIV-1 Tat and coactivator PCAF association., Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C, Wang Z, Zhou MM, J Am Chem Soc. 2005 Mar 2;127(8):2376-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15724976 15724976]

[[Category: Histone acetyltransferase]]

[[Category: Homo sapiens]]

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[[Category: nmr-structure]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:01:41 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1wug.gif|left|200px]]<br /><applet load="1wug" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1wug.gif|left|200px]]
-caption="1wug" />
-'''complex structure of PCAF bromodomain with small chemical ligand NP1'''<br />
+ {{Structure
+|PDB= 1wug |SIZE=350|CAPTION= <scene name='initialview01'>1wug</scene>
+|SITE=
+|LIGAND= <scene name='pdbligand=NP1:N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE'>NP1</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48]
+|GENE= PCAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''complex structure of PCAF bromodomain with small chemical ligand NP1'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-WUG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NP1:'>NP1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUG OCA].
+WUG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUG OCA].
 ==Reference==
-Selective small molecules blocking HIV-1 Tat and coactivator PCAF association., Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C, Wang Z, Zhou MM, J Am Chem Soc. 2005 Mar 2;127(8):2376-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15724976 15724976]
+Selective small molecules blocking HIV-1 Tat and coactivator PCAF association., Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C, Wang Z, Zhou MM, J Am Chem Soc. 2005 Mar 2;127(8):2376-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15724976 15724976]
 [[Category: Histone acetyltransferase]]
 [[Category: Homo sapiens]]
@@ Line 28: / Line 37: @@
 [[Category: nmr-structure]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:48:13 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:01:41 2008''