1wum: Difference between revisions

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[[Image:1wum.gif|left|200px]]<br /><applet load="1wum" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wum.gif|left|200px]]
caption="1wum" />
 
'''Complex structure of PCAF bromodomain with small chemical ligand NP2'''<br />
{{Structure
|PDB= 1wum |SIZE=350|CAPTION= <scene name='initialview01'>1wum</scene>
|SITE=  
|LIGAND= <scene name='pdbligand=NP2:N-(3-AMINOPROPYL)-2-NITROBENZENAMINE'>NP2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48]
|GENE=  
}}
 
'''Complex structure of PCAF bromodomain with small chemical ligand NP2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WUM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NP2:'>NP2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUM OCA].  
1WUM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUM OCA].  


==Reference==
==Reference==
Selective small molecules blocking HIV-1 Tat and coactivator PCAF association., Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C, Wang Z, Zhou MM, J Am Chem Soc. 2005 Mar 2;127(8):2376-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15724976 15724976]
Selective small molecules blocking HIV-1 Tat and coactivator PCAF association., Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C, Wang Z, Zhou MM, J Am Chem Soc. 2005 Mar 2;127(8):2376-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15724976 15724976]
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: np2]]
[[Category: np2]]


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