1wx2: Difference between revisions

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[[Image:1wx2.gif|left|200px]]<br /><applet load="1wx2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wx2.gif|left|200px]]
caption="1wx2, resolution 1.80&Aring;" />
 
'''Crystal Structure of the oxy-form of the copper-bound Streptomyces castaneoglobisporus tyrosinase complexed with a caddie protein prepared by the addition of hydrogenperoxide'''<br />
{{Structure
|PDB= 1wx2 |SIZE=350|CAPTION= <scene name='initialview01'>1wx2</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene> and <scene name='pdbligand=PER:PEROXIDE ION'>PER</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Monophenol_monooxygenase Monophenol monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1]
|GENE= tyrc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus]), orf378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus])
}}
 
'''Crystal Structure of the oxy-form of the copper-bound Streptomyces castaneoglobisporus tyrosinase complexed with a caddie protein prepared by the addition of hydrogenperoxide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WX2 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus] with <scene name='pdbligand=CU:'>CU</scene>, <scene name='pdbligand=NO3:'>NO3</scene> and <scene name='pdbligand=PER:'>PER</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Monophenol_monooxygenase Monophenol monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WX2 OCA].  
1WX2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WX2 OCA].  


==Reference==
==Reference==
Crystallographic evidence that the dinuclear copper center of tyrosinase is flexible during catalysis., Matoba Y, Kumagai T, Yamamoto A, Yoshitsu H, Sugiyama M, J Biol Chem. 2006 Mar 31;281(13):8981-90. Epub 2006 Jan 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16436386 16436386]
Crystallographic evidence that the dinuclear copper center of tyrosinase is flexible during catalysis., Matoba Y, Kumagai T, Yamamoto A, Yoshitsu H, Sugiyama M, J Biol Chem. 2006 Mar 31;281(13):8981-90. Epub 2006 Jan 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16436386 16436386]
[[Category: Monophenol monooxygenase]]
[[Category: Monophenol monooxygenase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: tyrosinase]]
[[Category: tyrosinase]]


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