1wze: Difference between revisions

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[[Image:1wze.gif|left|200px]]<br /><applet load="1wze" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wze.gif|left|200px]]
caption="1wze, resolution 2.00&Aring;" />
 
'''Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus'''<br />
{{Structure
|PDB= 1wze |SIZE=350|CAPTION= <scene name='initialview01'>1wze</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37]
|GENE= mdh ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
}}
 
'''Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WZE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZE OCA].  
1WZE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZE OCA].  


==Reference==
==Reference==
Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus., Kelly CA, Nishiyama M, Ohnishi Y, Beppu T, Birktoft JJ, Biochemistry. 1993 Apr 20;32(15):3913-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8471603 8471603]
Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus., Kelly CA, Nishiyama M, Ohnishi Y, Beppu T, Birktoft JJ, Biochemistry. 1993 Apr 20;32(15):3913-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8471603 8471603]
[[Category: Malate dehydrogenase]]
[[Category: Malate dehydrogenase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: seven amino acid residues mutant]]
[[Category: seven amino acid residues mutant]]


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