1x12: Difference between revisions

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[[Image:1x12.gif|left|200px]]<br /><applet load="1x12" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1x12.gif|left|200px]]
caption="1x12, resolution 2.0&Aring;" />
 
'''Structure of Mutant Pyrrolidone Carboxyl Peptidase (E192D) from a Hyperthermophile, Pyrococcus furiosus'''<br />
{{Structure
|PDB= 1x12 |SIZE=350|CAPTION= <scene name='initialview01'>1x12</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Pyroglutamyl-peptidase_I Pyroglutamyl-peptidase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.3 3.4.19.3]
|GENE=
}}
 
'''Structure of Mutant Pyrrolidone Carboxyl Peptidase (E192D) from a Hyperthermophile, Pyrococcus furiosus'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1X12 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Active as [http://en.wikipedia.org/wiki/Pyroglutamyl-peptidase_I Pyroglutamyl-peptidase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.3 3.4.19.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X12 OCA].  
1X12 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X12 OCA].  


==Reference==
==Reference==
Completely buried, non-ion-paired glutamic acid contributes favorably to the conformational stability of pyrrolidone carboxyl peptidases from hyperthermophiles., Kaushik JK, Iimura S, Ogasahara K, Yamagata Y, Segawa S, Yutani K, Biochemistry. 2006 Jun 13;45(23):7100-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16752900 16752900]
Completely buried, non-ion-paired glutamic acid contributes favorably to the conformational stability of pyrrolidone carboxyl peptidases from hyperthermophiles., Kaushik JK, Iimura S, Ogasahara K, Yamagata Y, Segawa S, Yutani K, Biochemistry. 2006 Jun 13;45(23):7100-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16752900 16752900]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyroglutamyl-peptidase I]]
[[Category: Pyroglutamyl-peptidase I]]
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[[Category: stability of protein]]
[[Category: stability of protein]]


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