1x2r: Difference between revisions

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[[Image:1x2r.gif|left|200px]]<br /><applet load="1x2r" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1x2r.gif|left|200px]]
caption="1x2r, resolution 1.7&Aring;" />
 
'''Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2'''<br />
{{Structure
|PDB= 1x2r |SIZE=350|CAPTION= <scene name='initialview01'>1x2r</scene>, resolution 1.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|ACTIVITY=
|GENE=
}}
 
'''Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1X2R is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X2R OCA].  
1X2R is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X2R OCA].  


==Reference==
==Reference==
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer., Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M, Mol Cell. 2006 Mar 3;21(5):689-700. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16507366 16507366]
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer., Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M, Mol Cell. 2006 Mar 3;21(5):689-700. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16507366 16507366]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: SO4]]
[[Category: SO4]]
[[Category: beta propeller]]
[[Category: beta propeller]]
[[Category: national project on protein structural and functional analyses]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: structural genomic]]


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