3ale: Difference between revisions

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[[Image:3ale.png|left|200px]]
{{STRUCTURE_3ale|  PDB=3ale  |  SCENE=  }}  
{{STRUCTURE_3ale|  PDB=3ale  |  SCENE=  }}  
===A type III polyketide synthase that produces diarylheptanoid===
===A type III polyketide synthase that produces diarylheptanoid===
{{ABSTRACT_PUBMED_21041675}}


{{ABSTRACT_PUBMED_021041675}}
==Function==
[[http://www.uniprot.org/uniprot/CUS_ORYSJ CUS_ORYSJ]] Plant-specific type III polyketide synthase (PKS) that catalyzes the one-pot formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin by the condensation of two molecules of 4-coumaroyl-CoA and one molecule of malonyl-CoA.<ref>PMID:21041675</ref> 


==About this Structure==
==About this Structure==
[[3ale]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ALE OCA].  
[[3ale]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ALE OCA].  
[[Category: Oryza sativa]]
 
==Reference==
<ref group="xtra">PMID:021041675</ref><references group="xtra"/><references/>
[[Category: Japanese rice]]
[[Category: Abe, I.]]
[[Category: Abe, I.]]
[[Category: Kato, R.]]
[[Category: Kato, R.]]

Revision as of 05:53, 22 January 2014

Template:STRUCTURE 3ale

A type III polyketide synthase that produces diarylheptanoid

Template:ABSTRACT PUBMED 21041675

Function

[CUS_ORYSJ] Plant-specific type III polyketide synthase (PKS) that catalyzes the one-pot formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin by the condensation of two molecules of 4-coumaroyl-CoA and one molecule of malonyl-CoA.[1]

About this Structure

3ale is a 4 chain structure with sequence from Japanese rice. Full crystallographic information is available from OCA.

Reference

  1. Morita H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I. Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19778-83. Epub 2010 Nov 1. PMID:21041675 doi:https://dx.doi.org/10.1073/pnas.1011499107
  1. ↑ Morita H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I. Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19778-83. Epub 2010 Nov 1. PMID:21041675 doi:https://dx.doi.org/10.1073/pnas.1011499107

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