3bap: Difference between revisions
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{{STRUCTURE_3bap| PDB=3bap | SCENE= }} | {{STRUCTURE_3bap| PDB=3bap | SCENE= }} | ||
===Crystal Structure of the 25 kDa Subunit of Human Cleavage Factor Im=== | ===Crystal Structure of the 25 kDa Subunit of Human Cleavage Factor Im=== | ||
{{ABSTRACT_PUBMED_18445629}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CPSF5_HUMAN CPSF5_HUMAN]] Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:20479262</ref> <ref>PMID:21295486</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018445629</ref><references group="xtra"/> | <ref group="xtra">PMID:018445629</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Coseno, M.]] | [[Category: Coseno, M.]] | ||
