1xdu: Difference between revisions

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[[Image:1xdu.gif|left|200px]]<br /><applet load="1xdu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xdu.gif|left|200px]]
caption="1xdu, resolution 2.70&Aring;" />
 
'''Crystal structure of Aclacinomycin-10-hydroxylase (RdmB) in complex with Sinefungin (SFG)'''<br />
{{Structure
|PDB= 1xdu |SIZE=350|CAPTION= <scene name='initialview01'>1xdu</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene> and <scene name='pdbligand=SFG:ADENOSYL-ORNITHINE'>SFG</scene>
|ACTIVITY=
|GENE= rdmb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1924 Streptomyces purpurascens])
}}
 
'''Crystal structure of Aclacinomycin-10-hydroxylase (RdmB) in complex with Sinefungin (SFG)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XDU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_purpurascens Streptomyces purpurascens] with <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=SFG:'>SFG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XDU OCA].  
1XDU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_purpurascens Streptomyces purpurascens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XDU OCA].  


==Reference==
==Reference==
Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor., Jansson A, Koskiniemi H, Erola A, Wang J, Mantsala P, Schneider G, Niemi J, J Biol Chem. 2005 Feb 4;280(5):3636-44. Epub 2004 Nov 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15548527 15548527]
Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor., Jansson A, Koskiniemi H, Erola A, Wang J, Mantsala P, Schneider G, Niemi J, J Biol Chem. 2005 Feb 4;280(5):3636-44. Epub 2004 Nov 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15548527 15548527]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Streptomyces purpurascens]]
[[Category: Streptomyces purpurascens]]
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[[Category: anthracycline; hydroxylase; s-adenosyl-l-methionine analogue; sinefungin; streptomyces; polyketide antibiotics; divergent evolution]]
[[Category: anthracycline; hydroxylase; s-adenosyl-l-methionine analogue; sinefungin; streptomyces; polyketide antibiotics; divergent evolution]]


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