1xfa: Difference between revisions

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[[Image:1xfa.gif|left|200px]]<br /><applet load="1xfa" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xfa.gif|left|200px]]
caption="1xfa, resolution 3.10&Aring;" />
 
'''Structure of NBD1 from murine CFTR- F508R mutant'''<br />
{{Structure
|PDB= 1xfa |SIZE=350|CAPTION= <scene name='initialview01'>1xfa</scene>, resolution 3.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
|ACTIVITY=
|GENE= Cftr, Abcc7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Structure of NBD1 from murine CFTR- F508R mutant'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XFA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ATP:'>ATP</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XFA OCA].  
1XFA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XFA OCA].  


==Reference==
==Reference==
Side chain and backbone contributions of Phe508 to CFTR folding., Thibodeau PH, Brautigam CA, Machius M, Thomas PJ, Nat Struct Mol Biol. 2005 Jan;12(1):10-6. Epub 2004 Dec 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15619636 15619636]
Side chain and backbone contributions of Phe508 to CFTR folding., Thibodeau PH, Brautigam CA, Machius M, Thomas PJ, Nat Struct Mol Biol. 2005 Jan;12(1):10-6. Epub 2004 Dec 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15619636 15619636]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: CL]]
[[Category: CL]]
[[Category: MG]]
[[Category: MG]]
[[Category: abc transporters]]
[[Category: abc transporter]]
[[Category: atp]]
[[Category: atp]]
[[Category: cystic fibrosis]]
[[Category: cystic fibrosis]]
[[Category: nucleotide-binding domain]]
[[Category: nucleotide-binding domain]]


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