1xff: Difference between revisions

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[[Image:1xff.jpg|left|200px]]<br /><applet load="1xff" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xff.jpg|left|200px]]
caption="1xff, resolution 1.80&Aring;" />
 
'''Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate'''<br />
{{Structure
|PDB= 1xff |SIZE=350|CAPTION= <scene name='initialview01'>1xff</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene> and <scene name='pdbligand=GLU:GLUTAMIC ACID'>GLU</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glutamine--fructose-6-phosphate_transaminase_(isomerizing) Glutamine--fructose-6-phosphate transaminase (isomerizing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.16 2.6.1.16]
|GENE= GLMS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XFF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=GLU:'>GLU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1GDO. Active as [http://en.wikipedia.org/wiki/Glutamine--fructose-6-phosphate_transaminase_(isomerizing) Glutamine--fructose-6-phosphate transaminase (isomerizing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.16 2.6.1.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XFF OCA].  
1XFF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry 1GDO. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XFF OCA].  


==Reference==
==Reference==
Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 A crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase., Isupov MN, Obmolova G, Butterworth S, Badet-Denisot MA, Badet B, Polikarpov I, Littlechild JA, Teplyakov A, Structure. 1996 Jul 15;4(7):801-10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8805567 8805567]
Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 A crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase., Isupov MN, Obmolova G, Butterworth S, Badet-Denisot MA, Badet B, Polikarpov I, Littlechild JA, Teplyakov A, Structure. 1996 Jul 15;4(7):801-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8805567 8805567]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Glutamine--fructose-6-phosphate transaminase (isomerizing)]]
[[Category: Glutamine--fructose-6-phosphate transaminase (isomerizing)]]
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[[Category: complex (transferase/inhibitor); glutamine amidotransferase]]
[[Category: complex (transferase/inhibitor); glutamine amidotransferase]]


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