1xk9: Difference between revisions

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[[Image:1xk9.gif|left|200px]]<br /><applet load="1xk9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xk9.gif|left|200px]]
caption="1xk9, resolution 2.1&Aring;" />
 
'''Pseudomanas exotoxin A in complex with the PJ34 inhibitor'''<br />
{{Structure
|PDB= 1xk9 |SIZE=350|CAPTION= <scene name='initialview01'>1xk9</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=P34:N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE'>P34</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(+)--diphthamide_ADP-ribosyltransferase NAD(+)--diphthamide ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.36 2.4.2.36]
|GENE=
}}
 
'''Pseudomanas exotoxin A in complex with the PJ34 inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XK9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] with <scene name='pdbligand=P34:'>P34</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/NAD(+)--diphthamide_ADP-ribosyltransferase NAD(+)--diphthamide ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.36 2.4.2.36] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XK9 OCA].  
1XK9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XK9 OCA].  


==Reference==
==Reference==
Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa., Yates SP, Taylor PL, Jorgensen R, Ferraris D, Zhang J, Andersen GR, Merrill AR, Biochem J. 2005 Feb 1;385(Pt 3):667-75. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15458385 15458385]
Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa., Yates SP, Taylor PL, Jorgensen R, Ferraris D, Zhang J, Andersen GR, Merrill AR, Biochem J. 2005 Feb 1;385(Pt 3):667-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15458385 15458385]
[[Category: NAD(+)--diphthamide ADP-ribosyltransferase]]
[[Category: NAD(+)--diphthamide ADP-ribosyltransferase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: toxin]]
[[Category: toxin]]


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