1xnz: Difference between revisions

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[[Image:1xnz.jpg|left|200px]]<br /><applet load="1xnz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xnz.jpg|left|200px]]
caption="1xnz, resolution 1.52&Aring;" />
 
'''Crystal Structure of Mn(II) form of E. coli. Methionine Aminopeptidase in complex with 5-(2-chlorophenyl)furan-2-carboxylic acid'''<br />
{{Structure
|PDB= 1xnz |SIZE=350|CAPTION= <scene name='initialview01'>1xnz</scene>, resolution 1.52&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=FCD:5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID'>FCD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18]
|GENE= map ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal Structure of Mn(II) form of E. coli. Methionine Aminopeptidase in complex with 5-(2-chlorophenyl)furan-2-carboxylic acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XNZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=FCD:'>FCD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNZ OCA].  
1XNZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNZ OCA].  


==Reference==
==Reference==
Metalloform-selective inhibitors of escherichia coli methionine aminopeptidase and X-ray structure of a Mn(II)-form enzyme complexed with an inhibitor., Ye QZ, Xie SX, Huang M, Huang WJ, Lu JP, Ma ZQ, J Am Chem Soc. 2004 Nov 3;126(43):13940-1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15506752 15506752]
Metalloform-selective inhibitors of escherichia coli methionine aminopeptidase and X-ray structure of a Mn(II)-form enzyme complexed with an inhibitor., Ye QZ, Xie SX, Huang M, Huang WJ, Lu JP, Ma ZQ, J Am Chem Soc. 2004 Nov 3;126(43):13940-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15506752 15506752]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methionyl aminopeptidase]]
[[Category: Methionyl aminopeptidase]]
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[[Category: structure]]
[[Category: structure]]


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