1xu8: Difference between revisions

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[[Image:1xu8.gif|left|200px]]<br /><applet load="1xu8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xu8.gif|left|200px]]
caption="1xu8, resolution 2.8&Aring;" />
 
'''The 2.8 A structure of a tumour suppressing serpin'''<br />
{{Structure
|PDB= 1xu8 |SIZE=350|CAPTION= <scene name='initialview01'>1xu8</scene>, resolution 2.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|ACTIVITY=
|GENE= SERPINB5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''The 2.8 A structure of a tumour suppressing serpin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XU8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XU8 OCA].  
1XU8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XU8 OCA].  


==Reference==
==Reference==
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix., Law RH, Irving JA, Buckle AM, Ruzyla K, Buzza M, Bashtannyk-Puhalovich TA, Beddoe TC, Nguyen K, Worrall DM, Bottomley SP, Bird PI, Rossjohn J, Whisstock JC, J Biol Chem. 2005 Jun 10;280(23):22356-64. Epub 2005 Mar 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15760906 15760906]
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix., Law RH, Irving JA, Buckle AM, Ruzyla K, Buzza M, Bashtannyk-Puhalovich TA, Beddoe TC, Nguyen K, Worrall DM, Bottomley SP, Bird PI, Rossjohn J, Whisstock JC, J Biol Chem. 2005 Jun 10;280(23):22356-64. Epub 2005 Mar 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15760906 15760906]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tumor suppressor]]
[[Category: tumor suppressor]]


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