2r0y: Difference between revisions
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{{STRUCTURE_2r0y| PDB=2r0y | SCENE= }} | {{STRUCTURE_2r0y| PDB=2r0y | SCENE= }} | ||
===Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide=== | ===Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide=== | ||
{{ABSTRACT_PUBMED_17803945}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RSC4_YEAST RSC4_YEAST]] Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.<ref>PMID:8980231</ref> <ref>PMID:10025404</ref> <ref>PMID:10329629</ref> <ref>PMID:12183366</ref> <ref>PMID:12072455</ref> <ref>PMID:12697820</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:017803945</ref><references group="xtra"/> | <ref group="xtra">PMID:017803945</ref><references group="xtra"/><references/> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Cairns, B R.]] | [[Category: Cairns, B R.]] | ||
