1y3g: Difference between revisions

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[[Image:1y3g.gif|left|200px]]<br /><applet load="1y3g" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1y3g.gif|left|200px]]
caption="1y3g, resolution 2.10&Aring;" />
 
'''Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin'''<br />
{{Structure
|PDB= 1y3g |SIZE=350|CAPTION= <scene name='initialview01'>1y3g</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene> and <scene name='pdbligand=3PL:3-PHENYLPROPANAL'>3PL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27]
|GENE=
}}
 
'''Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Y3G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=DMS:'>DMS</scene> and <scene name='pdbligand=3PL:'>3PL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3G OCA].  
1Y3G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3G OCA].  


==Reference==
==Reference==
Structural analysis of silanediols as transition-state-analogue inhibitors of the benchmark metalloprotease thermolysin., Juers DH, Kim J, Matthews BW, Sieburth SM, Biochemistry. 2005 Dec 20;44(50):16524-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16342943 16342943]
Structural analysis of silanediols as transition-state-analogue inhibitors of the benchmark metalloprotease thermolysin., Juers DH, Kim J, Matthews BW, Sieburth SM, Biochemistry. 2005 Dec 20;44(50):16524-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16342943 16342943]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: thermolysin]]
[[Category: thermolysin]]


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