1y75: Difference between revisions

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[[Image:1y75.gif|left|200px]]<br /><applet load="1y75" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1y75.gif|left|200px]]
caption="1y75, resolution 2.30&Aring;" />
 
'''A new form of catalytically inactive phospholipase A2 with an unusual disulphide bridge Cys 32- Cys 49 reveals recognition for N-acetylglucosmine'''<br />
{{Structure
|PDB= 1y75 |SIZE=350|CAPTION= <scene name='initialview01'>1y75</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4]
|GENE=
}}
 
'''A new form of catalytically inactive phospholipase A2 with an unusual disulphide bridge Cys 32- Cys 49 reveals recognition for N-acetylglucosmine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Y75 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y75 OCA].  
1Y75 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y75 OCA].  


==Reference==
==Reference==
Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 A resolution reveals the presence of a new PLA2-like protein with a novel cys 32-Cys 49 disulphide bridge with a bound sugar at the substrate-binding site., Jabeen T, Singh N, Singh RK, Jasti J, Sharma S, Kaur P, Srinivasan A, Singh TP, Proteins. 2006 Feb 1;62(2):329-37. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16287060 16287060]
Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 A resolution reveals the presence of a new PLA2-like protein with a novel cys 32-Cys 49 disulphide bridge with a bound sugar at the substrate-binding site., Jabeen T, Singh N, Singh RK, Jasti J, Sharma S, Kaur P, Srinivasan A, Singh TP, Proteins. 2006 Feb 1;62(2):329-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16287060 16287060]
[[Category: Naja sagittifera]]
[[Category: Naja sagittifera]]
[[Category: Phospholipase A(2)]]
[[Category: Phospholipase A(2)]]
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[[Category: molecular association]]
[[Category: molecular association]]


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