1y9r: Difference between revisions

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[[Image:1y9r.gif|left|200px]]<br /><applet load="1y9r" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1y9r.gif|left|200px]]
caption="1y9r, resolution 1.96&Aring;" />
 
'''Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone and harboring the S810L mutation responsible for a severe form of hypertension'''<br />
{{Structure
|PDB= 1y9r |SIZE=350|CAPTION= <scene name='initialview01'>1y9r</scene>, resolution 1.96&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=1CA:DESOXYCORTICOSTERONE'>1CA</scene>
|ACTIVITY=
|GENE= NR3C2, MCR, MLR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone and harboring the S810L mutation responsible for a severe form of hypertension'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Y9R is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=1CA:'>1CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y9R OCA].  
1Y9R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y9R OCA].  


==Reference==
==Reference==
Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension., Fagart J, Huyet J, Pinon GM, Rochel M, Mayer C, Rafestin-Oblin ME, Nat Struct Mol Biol. 2005 Jun;12(6):554-5. Epub 2005 May 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15908963 15908963]
Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension., Fagart J, Huyet J, Pinon GM, Rochel M, Mayer C, Rafestin-Oblin ME, Nat Struct Mol Biol. 2005 Jun;12(6):554-5. Epub 2005 May 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15908963 15908963]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: mineralocorticoid receptor; steroid receptor; nuclear recept; transcription regulation; activating mutation; hypertension]]
[[Category: mineralocorticoid receptor; steroid receptor; nuclear recept; transcription regulation; activating mutation; hypertension]]


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