1yci: Difference between revisions

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[[Image:1yci.gif|left|200px]]<br /><applet load="1yci" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yci.gif|left|200px]]
caption="1yci, resolution 2.70&Aring;" />
 
'''Factor inhibiting HIF-1 alpha in complex with N-(carboxycarbonyl)-D-phenylalanine'''<br />
{{Structure
|PDB= 1yci |SIZE=350|CAPTION= <scene name='initialview01'>1yci</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NDF:N-(CARBOXYCARBONYL)-D-PHENYLALANINE'>NDF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Peptide-aspartate_beta-dioxygenase Peptide-aspartate beta-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.16 1.14.11.16]
|GENE= HIF1AN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Factor inhibiting HIF-1 alpha in complex with N-(carboxycarbonyl)-D-phenylalanine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YCI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FE2:'>FE2</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=NDF:'>NDF</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peptide-aspartate_beta-dioxygenase Peptide-aspartate beta-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.16 1.14.11.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YCI OCA].  
1YCI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YCI OCA].  


==Reference==
==Reference==
Selective inhibition of factor inhibiting hypoxia-inducible factor., McDonough MA, McNeill LA, Tilliet M, Papamicael CA, Chen QY, Banerji B, Hewitson KS, Schofield CJ, J Am Chem Soc. 2005 Jun 1;127(21):7680-1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15913349 15913349]
Selective inhibition of factor inhibiting hypoxia-inducible factor., McDonough MA, McNeill LA, Tilliet M, Papamicael CA, Chen QY, Banerji B, Hewitson KS, Schofield CJ, J Am Chem Soc. 2005 Jun 1;127(21):7680-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15913349 15913349]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptide-aspartate beta-dioxygenase]]
[[Category: Peptide-aspartate beta-dioxygenase]]
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[[Category: transcription]]
[[Category: transcription]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:21:08 2008''