1yhv: Difference between revisions

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[[Image:1yhv.gif|left|200px]]<br /><applet load="1yhv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yhv.gif|left|200px]]
caption="1yhv, resolution 1.80&Aring;" />
 
'''Crystal Structure of PAK1 kinase domain with two point mutations (K299R, T423E)'''<br />
{{Structure
|PDB= 1yhv |SIZE=350|CAPTION= <scene name='initialview01'>1yhv</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= PAK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of PAK1 kinase domain with two point mutations (K299R, T423E)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YHV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YHV OCA].  
1YHV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YHV OCA].  


==Reference==
==Reference==
The active conformation of the PAK1 kinase domain., Lei M, Robinson MA, Harrison SC, Structure. 2005 May;13(5):769-78. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15893667 15893667]
The active conformation of the PAK1 kinase domain., Lei M, Robinson MA, Harrison SC, Structure. 2005 May;13(5):769-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15893667 15893667]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: kinase; active conformation; activation loop; atp binding site]]
[[Category: kinase; active conformation; activation loop; atp binding site]]


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