3e17: Difference between revisions
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{{STRUCTURE_3e17| PDB=3e17 | SCENE= }} | {{STRUCTURE_3e17| PDB=3e17 | SCENE= }} | ||
===Crystal structure of the second PDZ domain from human Zona Occludens-2=== | |||
{{ABSTRACT_PUBMED_19342771}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/ZO2_HUMAN ZO2_HUMAN]] Defects in TJP2 are involved in familial hypercholanemia (FHCA) [MIM:[http://omim.org/entry/607748 607748]]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption.<ref>PMID:12704386</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ZO2_HUMAN ZO2_HUMAN]] Plays a role in tight junctions and adherens junctions. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019342771</ref><references group="xtra"/> | <ref group="xtra">PMID:019342771</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chen, H.]] | [[Category: Chen, H.]] | ||
