1yqn: Difference between revisions

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[[Image:1yqn.gif|left|200px]]<br /><applet load="1yqn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yqn.gif|left|200px]]
caption="1yqn, resolution 3.11&Aring;" />
 
'''E. coli ispF double mutant'''<br />
{{Structure
|PDB= 1yqn |SIZE=350|CAPTION= <scene name='initialview01'>1yqn</scene>, resolution 3.11&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=CDP:CYTIDINE-5'-DIPHOSPHATE'>CDP</scene> and <scene name='pdbligand=GPP:GERANYL DIPHOSPHATE'>GPP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12]
|GENE= ispF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''E. coli ispF double mutant'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YQN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=CDP:'>CDP</scene> and <scene name='pdbligand=GPP:'>GPP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQN OCA].  
1YQN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQN OCA].  


==Reference==
==Reference==
A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate., Sgraja T, Kemp LE, Ramsden N, Hunter WN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1;61(Pt, 7):625-9. Epub 2005 Jun 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16511114 16511114]
A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate., Sgraja T, Kemp LE, Ramsden N, Hunter WN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1;61(Pt, 7):625-9. Epub 2005 Jun 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511114 16511114]
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: alpha-beta protein]]
[[Category: alpha-beta protein]]


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