1yt9: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1yt9.jpg|left|200px]]<br /><applet load="1yt9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yt9.jpg|left|200px]]
caption="1yt9, resolution 3.00&Aring;" />
 
'''HIV Protease with oximinoarylsulfonamide bound'''<br />
{{Structure
|PDB= 1yt9 |SIZE=350|CAPTION= <scene name='initialview01'>1yt9</scene>, resolution 3.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=OIS:(S)-N-((2S,3R)-3-HYDROXY-4-(4-((E)-(HYDROXYIMINO)METHYL)-N-ISOBUTYLPHENYLSULFONAMIDO)-1-PHENYLBUTAN-2-YL)-3-METHYL-2-(3-((2-METHYLTHIAZOL-4-YL)METHYL)-2-OXOIMIDAZOLIDIN-1-YL)BUTANAMIDE'>OIS</scene>
|ACTIVITY=
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''HIV Protease with oximinoarylsulfonamide bound'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1YT9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=OIS:'>OIS</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YT9 OCA].  
1YT9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YT9 OCA].  


==Reference==
==Reference==
Oximinoarylsulfonamides as potent HIV protease inhibitors., Yeung CM, Klein LL, Flentge CA, Randolph JT, Zhao C, Sun M, Dekhtyar T, Stoll VS, Kempf DJ, Bioorg Med Chem Lett. 2005 May 2;15(9):2275-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15837308 15837308]
Oximinoarylsulfonamides as potent HIV protease inhibitors., Yeung CM, Klein LL, Flentge CA, Randolph JT, Zhao C, Sun M, Dekhtyar T, Stoll VS, Kempf DJ, Bioorg Med Chem Lett. 2005 May 2;15(9):2275-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15837308 15837308]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 24: Line 33:
[[Category: OIS]]
[[Category: OIS]]
[[Category: hiv protease]]
[[Category: hiv protease]]
[[Category: oximinoarylsulfonamides]]
[[Category: oximinoarylsulfonamide]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:08:54 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:27:16 2008''