1yy4: Difference between revisions

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[[Image:1yy4.gif|left|200px]]<br /><applet load="1yy4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yy4.gif|left|200px]]
caption="1yy4, resolution 2.70&Aring;" />
 
'''Crystal structure of estrogen receptor beta complexed with 1-chloro-6-(4-hydroxy-phenyl)-naphthalen-2-ol'''<br />
{{Structure
|PDB= 1yy4 |SIZE=350|CAPTION= <scene name='initialview01'>1yy4</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=4NA:1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL'>4NA</scene>
|ACTIVITY=
|GENE= ESR2, ESTRB, NR3A2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of estrogen receptor beta complexed with 1-chloro-6-(4-hydroxy-phenyl)-naphthalen-2-ol'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YY4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=4NA:'>4NA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY4 OCA].  
1YY4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY4 OCA].  


==Reference==
==Reference==
ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity., Mewshaw RE, Edsall RJ Jr, Yang C, Manas ES, Xu ZB, Henderson RA, Keith JC Jr, Harris HA, J Med Chem. 2005 Jun 16;48(12):3953-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15943471 15943471]
ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity., Mewshaw RE, Edsall RJ Jr, Yang C, Manas ES, Xu ZB, Henderson RA, Keith JC Jr, Harris HA, J Med Chem. 2005 Jun 16;48(12):3953-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15943471 15943471]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transcription factor]]
[[Category: transcription factor]]


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