1yyu: Difference between revisions

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[[Image:1yyu.gif|left|200px]]<br /><applet load="1yyu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yyu.gif|left|200px]]
caption="1yyu, resolution 2.95&Aring;" />
 
'''D100E Trichodiene Synthase: Complex With Mg, Pyrophosphate, and (4S)-7-azabisabolene'''<br />
{{Structure
|PDB= 1yyu |SIZE=350|CAPTION= <scene name='initialview01'>1yyu</scene>, resolution 2.95&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RAZ:(1R)-N,4-DIMETHYL-N-(4-METHYLPENT-3-ENYL)CYCLOHEX-3-ENAMINIUM'>RAZ</scene>, <scene name='pdbligand=SAZ:(1S)-N,4-DIMETHYL-N-(4-METHYLPENT-3-ENYL)CYCLOHEX-3-ENAMINIUM'>SAZ</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Trichodiene_synthase Trichodiene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.6 4.2.3.6]
|GENE= TRI5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5514 Fusarium sporotrichioides])
}}
 
'''D100E Trichodiene Synthase: Complex With Mg, Pyrophosphate, and (4S)-7-azabisabolene'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YYU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Fusarium_sporotrichioides Fusarium sporotrichioides] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=RAZ:'>RAZ</scene>, <scene name='pdbligand=SAZ:'>SAZ</scene>, <scene name='pdbligand=POP:'>POP</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trichodiene_synthase Trichodiene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.6 4.2.3.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YYU OCA].  
1YYU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Fusarium_sporotrichioides Fusarium sporotrichioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YYU OCA].  


==Reference==
==Reference==
Molecular recognition of the substrate diphosphate group governs product diversity in trichodiene synthase mutants., Vedula LS, Rynkiewicz MJ, Pyun HJ, Coates RM, Cane DE, Christianson DW, Biochemistry. 2005 Apr 26;44(16):6153-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15835903 15835903]
Molecular recognition of the substrate diphosphate group governs product diversity in trichodiene synthase mutants., Vedula LS, Rynkiewicz MJ, Pyun HJ, Coates RM, Cane DE, Christianson DW, Biochemistry. 2005 Apr 26;44(16):6153-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15835903 15835903]
[[Category: Fusarium sporotrichioides]]
[[Category: Fusarium sporotrichioides]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: terpenoid cyclase fold]]
[[Category: terpenoid cyclase fold]]


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