2m0y: Difference between revisions
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{{STRUCTURE_2m0y| PDB=2m0y | SCENE= }} | {{STRUCTURE_2m0y| PDB=2m0y | SCENE= }} | ||
===Solution structure of the SH3 domain of DOCK180=== | ===Solution structure of the SH3 domain of DOCK180=== | ||
{{ABSTRACT_PUBMED_23239367}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DOCK1_MOUSE DOCK1_MOUSE]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
