4ec2: Difference between revisions
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{{STRUCTURE_4ec2| PDB=4ec2 | SCENE= }} | {{STRUCTURE_4ec2| PDB=4ec2 | SCENE= }} | ||
===Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, complexed with ferrous=== | ===Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, complexed with ferrous=== | ||
{{ABSTRACT_PUBMED_23344952}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FRDA_YEAST FRDA_YEAST]] Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. Plays a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). Can store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. May be involved in regulation of the mitochondrial electron transport chain.<ref>PMID:9180083</ref> <ref>PMID:9988680</ref> <ref>PMID:15961414</ref> <ref>PMID:16371422</ref> <ref>PMID:19884169</ref> <ref>PMID:17027502</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:023344952</ref><references group="xtra"/><references/> | ||
[[Category: Ferroxidase]] | [[Category: Ferroxidase]] | ||
[[Category: Saccharomyces cerevisiae s288c]] | [[Category: Saccharomyces cerevisiae s288c]] | ||
