2ly6: Difference between revisions

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[[Image:2ly6.png|left|200px]]
{{STRUCTURE_2ly6|  PDB=2ly6  |  SCENE=  }}  
{{STRUCTURE_2ly6|  PDB=2ly6  |  SCENE=  }}  
===Refined solution structure of recombinant brazzein at low temperature===
===Refined solution structure of recombinant brazzein at low temperature===
{{ABSTRACT_PUBMED_23349025}}


{{ABSTRACT_PUBMED_23349025}}
==Function==
[[http://www.uniprot.org/uniprot/DEF_PENBA DEF_PENBA]] Taste-modifying protein; sweet-tasting. It is 2000 sweeter than sucrose on a molar basis.<ref>PMID:15118082</ref>  Has a pH-specific antimicrobial activity against bacteria (B.subtilis, E.coli and S.aureus) and the fungus C.albicans.<ref>PMID:15118082</ref> 


==About this Structure==
==About this Structure==
[[2ly6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pentadiplandra_brazzeana Pentadiplandra brazzeana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY6 OCA].  
[[2ly6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pentadiplandra_brazzeana Pentadiplandra brazzeana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY6 OCA].  
==Reference==
<ref group="xtra">PMID:023349025</ref><references group="xtra"/><references/>
[[Category: Pentadiplandra brazzeana]]
[[Category: Pentadiplandra brazzeana]]
[[Category: Assadi-Porter, F M.]]
[[Category: Assadi-Porter, F M.]]

Revision as of 18:18, 19 June 2013

Template:STRUCTURE 2ly6

Refined solution structure of recombinant brazzein at low temperature

Template:ABSTRACT PUBMED 23349025

Function

[DEF_PENBA] Taste-modifying protein; sweet-tasting. It is 2000 sweeter than sucrose on a molar basis.[1] Has a pH-specific antimicrobial activity against bacteria (B.subtilis, E.coli and S.aureus) and the fungus C.albicans.[2]

About this Structure

2ly6 is a 1 chain structure with sequence from Pentadiplandra brazzeana. Full experimental information is available from OCA.

Reference

  1. Cornilescu CC, Cornilescu G, Rao H, Porter SF, Tonelli M, Derider ML, Markley JL, Assadi-Porter FM. Temperature-dependent conformational change affecting Tyr11 and sweetness loops of brazzein. Proteins. 2013 Jan 24. doi: 10.1002/prot.24259. PMID:23349025 doi:10.1002/prot.24259
  1. ↑ Yount NY, Yeaman MR. Multidimensional signatures in antimicrobial peptides. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8. Epub 2004 Apr 26. PMID:15118082 doi:10.1073/pnas.0401567101
  2. ↑ Yount NY, Yeaman MR. Multidimensional signatures in antimicrobial peptides. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8. Epub 2004 Apr 26. PMID:15118082 doi:10.1073/pnas.0401567101

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