1zkk: Difference between revisions

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[[Image:1zkk.gif|left|200px]]<br /><applet load="1zkk" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1zkk.gif|left|200px]]
caption="1zkk, resolution 1.45&Aring;" />
 
'''Crystal structure of hSET8 in ternary complex with H4 peptide (16-24) and AdoHcy'''<br />
{{Structure
|PDB= 1zkk |SIZE=350|CAPTION= <scene name='initialview01'>1zkk</scene>, resolution 1.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43]
|GENE= SET8, PRSET7, SET07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of hSET8 in ternary complex with H4 peptide (16-24) and AdoHcy'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ZKK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKK OCA].  
1ZKK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKK OCA].  


==Reference==
==Reference==
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase., Couture JF, Collazo E, Brunzelle JS, Trievel RC, Genes Dev. 2005 Jun 15;19(12):1455-65. Epub 2005 Jun 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15933070 15933070]
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase., Couture JF, Collazo E, Brunzelle JS, Trievel RC, Genes Dev. 2005 Jun 15;19(12):1455-65. Epub 2005 Jun 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15933070 15933070]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: pseudo-knot]]
[[Category: pseudo-knot]]


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