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[[Image:3ewb.png|left|200px]]
==Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes==
 
<StructureSection load='3ewb' size='340' side='right' caption='[[3ewb]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
{{STRUCTURE_3ewb|  PDB=3ewb  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ewb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes_serotype_4b_str._f2365 Listeria monocytogenes serotype 4b str. f2365]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWB FirstGlance]. <br>
===Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes===
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">leuA, LMOf2365_2010 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=265669 Listeria monocytogenes serotype 4b str. F2365])</td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-isopropylmalate_synthase 2-isopropylmalate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.13 2.3.3.13] </span></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ewb RCSB], [http://www.ebi.ac.uk/pdbsum/3ewb PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3ewb TOPSAN]</span></td></tr>
[[3ewb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes_serotype_4b_str._f2365 Listeria monocytogenes serotype 4b str. f2365]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWB OCA].  
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ewb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: 2-isopropylmalate synthase]]
[[Category: 2-isopropylmalate synthase]]
[[Category: Listeria monocytogenes serotype 4b str. f2365]]
[[Category: Listeria monocytogenes serotype 4b str. f2365]]
[[Category: Almo, S C.]]
[[Category: Almo, S C]]
[[Category: Burley, S K.]]
[[Category: Burley, S K]]
[[Category: Gilmore, M.]]
[[Category: Gilmore, M]]
[[Category: Hu, S.]]
[[Category: Hu, S]]
[[Category: Maletic, M.]]
[[Category: Maletic, M]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Ramagopal, U A.]]
[[Category: Ramagopal, U A]]
[[Category: Rodgers, L.]]
[[Category: Rodgers, L]]
[[Category: Toro, R.]]
[[Category: Toro, R]]
[[Category: Amino-acid biosynthesis]]
[[Category: Amino-acid biosynthesis]]
[[Category: Branched-chain amino acid biosynthesis]]
[[Category: Branched-chain amino acid biosynthesis]]
[[Category: Leua]]
[[Category: Leua]]
[[Category: Leucine biosynthesis]]
[[Category: Leucine biosynthesis]]
[[Category: New york sgx research center for structural genomic]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Nysgxrc]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Unknown function]]
[[Category: Unknown function]]