4i77: Difference between revisions
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{{STRUCTURE_4i77| PDB=4i77 | SCENE= }} | {{STRUCTURE_4i77| PDB=4i77 | SCENE= }} | ||
===Lebrikizumab Fab bound to IL-13=== | |||
{{ABSTRACT_PUBMED_23357170}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. | |||
==About this Structure== | ==About this Structure== | ||
