3vzd: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3vzd|  PDB=3vzd  |  SCENE=  }}
===Crystal structure of Sphingosine Kinase 1 with inhibitor and ADP===
{{ABSTRACT_PUBMED_23602659}}


The entry 3vzd is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/SPHK1_HUMAN SPHK1_HUMAN]] Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.<ref>PMID:20577214</ref>  


Authors: Min, X., Walker, N.P., Wang, Z.
==About this Structure==
[[3vzd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VZD OCA].  


Description: Crystal Structure of a lipid kinase with inhibitor and substrate
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Sphinganine kinase]]
[[Category: Min, X.]]
[[Category: Walker, N P.]]
[[Category: Wang, Z.]]
[[Category: Lipid kinase]]
[[Category: Transferase-inhibitor complex]]