4j2c: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4j2c|  PDB=4j2c  |  SCENE=  }}
===GARP-SNARE Interaction===
{{ABSTRACT_PUBMED_23932592}}


The entry 4j2c is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/STX6_HUMAN STX6_HUMAN]] Involved in intracellular vesicle trafficking. [[http://www.uniprot.org/uniprot/VPS51_HUMAN VPS51_HUMAN]] Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi networkl (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN.<ref>PMID:20685960</ref> 


Authors: Abascal-Palacios, G., Schindler, C., Rojas, A.L., Bonifacino, J.S., Hierro, A.
==About this Structure==
[[4j2c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2C OCA].  


Description: GARP-SNARE Interaction
==Reference==
<ref group="xtra">PMID:023932592</ref><references group="xtra"/><references/>
[[Category: Abascal-Palacios, G.]]
[[Category: Bonifacino, J S.]]
[[Category: Hierro, A.]]
[[Category: Rojas, A L.]]
[[Category: Schindler, C.]]
[[Category: Protein transport]]
[[Category: Tethering complex]]