1zyq: Difference between revisions

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[[Image:1zyq.gif|left|200px]]<br /><applet load="1zyq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1zyq.gif|left|200px]]
caption="1zyq, resolution 2.70&Aring;" />
 
'''T7 DNA polymerase in complex with 8oG and incoming ddATP'''<br />
{{Structure
|PDB= 1zyq |SIZE=350|CAPTION= <scene name='initialview01'>1zyq</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=DAD:2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE'>DAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7]
|GENE= 5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Bacteriophage T7]), trxA, fipA, tsnC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''T7 DNA polymerase in complex with 8oG and incoming ddATP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ZYQ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bacteriophage_t7 Bacteriophage t7] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=DAD:'>DAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYQ OCA].  
1ZYQ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacteriophage_t7 Bacteriophage t7] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYQ OCA].  


==Reference==
==Reference==
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine., Brieba LG, Kokoska RJ, Bebenek K, Kunkel TA, Ellenberger T, Structure. 2005 Nov;13(11):1653-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16271888 16271888]
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine., Brieba LG, Kokoska RJ, Bebenek K, Kunkel TA, Ellenberger T, Structure. 2005 Nov;13(11):1653-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16271888 16271888]
[[Category: Bacteriophage t7]]
[[Category: Bacteriophage t7]]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
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[[Category: fidelity]]
[[Category: fidelity]]


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