205d: Difference between revisions
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'''STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP''' | {{Structure | ||
|PDB= 205d |SIZE=350|CAPTION= <scene name='initialview01'>205d</scene>, resolution 2.640Å | |||
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'''STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
205D is a [ | 205D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=205D OCA]. | ||
==Reference== | ==Reference== | ||
Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:[http:// | Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7719854 7719854] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Baeyens, K J.]] | [[Category: Baeyens, K J.]] | ||
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[[Category: mismatched]] | [[Category: mismatched]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:41:56 2008'' | ||
Revision as of 13:42, 20 March 2008
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STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP
Overview
The crystal structure of the RNA dodecamer 5'-GGACUUUGGUCC-3' has been determined from X-ray diffraction data to 2.6 A resolution. This oligomer forms an asymmetric double helix in the crystal. Four consecutive non-Watson-Crick base-pairs are formed in the middle of the duplex including the first intrahelical U-U (or T-T) pairs observed in an oligonucleotide crystal structure. Two different conformations of U-U pairs are observed in the context of the surrounding sequence. One of these pairs is highly twisted, allowing a bound water to bridge across strands in the major groove. The crystal packing illustrates a new form of RNA helix-helix interaction.
About this Structure
205D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:7719854
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