216d: Difference between revisions
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[[Image:216d.jpg|left|200px]] | [[Image:216d.jpg|left|200px]] | ||
'''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN''' | {{Structure | ||
|PDB= 216d |SIZE=350|CAPTION= <scene name='initialview01'>216d</scene>, resolution 1.730Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=DMY:DISTAMYCIN+A'>DMY</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
216D is a [ | 216D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=216D OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http:// | Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7552741 7552741] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Chen, X.]] | [[Category: Chen, X.]] | ||
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[[Category: modified]] | [[Category: modified]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:42:12 2008'' | ||
Revision as of 13:42, 20 March 2008
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| 216d, resolution 1.730Å | |||||||||||||
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| Ligands: | DMY and MG | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Overview
Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.
About this Structure
216D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741
Page seeded by OCA on Thu Mar 20 15:42:12 2008
