252l: Difference between revisions

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[[Image:252l.jpg|left|200px]]<br /><applet load="252l" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:252l.jpg|left|200px]]
caption="252l, resolution 2.1&Aring;" />
 
'''GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS'''<br />
{{Structure
|PDB= 252l |SIZE=350|CAPTION= <scene name='initialview01'>252l</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=HED:2-HYDROXYETHYL DISULFIDE'>HED</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]
|GENE= GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Bacteriophage T4])
}}
 
'''GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
252L is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteriophage_t4 Bacteriophage t4] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=HED:'>HED</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=252L OCA].  
252L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteriophage_t4 Bacteriophage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=252L OCA].  


==Reference==
==Reference==
Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions., Baldwin E, Baase WA, Zhang X, Feher V, Matthews BW, J Mol Biol. 1998 Mar 27;277(2):467-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9514755 9514755]
Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions., Baldwin E, Baase WA, Zhang X, Feher V, Matthews BW, J Mol Biol. 1998 Mar 27;277(2):467-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9514755 9514755]
[[Category: Bacteriophage t4]]
[[Category: Bacteriophage t4]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
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[[Category: CL]]
[[Category: CL]]
[[Category: HED]]
[[Category: HED]]
[[Category: cavity mutants]]
[[Category: cavity mutant]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: ligand binding]]
[[Category: ligand binding]]
[[Category: multiple conformations]]
[[Category: multiple conformation]]
[[Category: o-glycosyl]]
[[Category: o-glycosyl]]
[[Category: protein design]]
[[Category: protein design]]
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[[Category: t4 lysozyme]]
[[Category: t4 lysozyme]]


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