2a0f: Difference between revisions

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[[Image:2a0f.gif|left|200px]]<br /><applet load="2a0f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a0f.gif|left|200px]]
caption="2a0f, resolution 2.9&Aring;" />
 
'''Structure of D236A mutant E. coli Aspartate Transcarbamoylase in presence of Phosphonoacetamide at 2.90 A resolution'''<br />
{{Structure
|PDB= 2a0f |SIZE=350|CAPTION= <scene name='initialview01'>2a0f</scene>, resolution 2.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=PCT:PHOSPHONOACETAMIDE'>PCT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartate_carbamoyltransferase Aspartate carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.2 2.1.3.2]
|GENE= pyrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), pyrI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Structure of D236A mutant E. coli Aspartate Transcarbamoylase in presence of Phosphonoacetamide at 2.90 A resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A0F is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=PCT:'>PCT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aspartate_carbamoyltransferase Aspartate carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.2 2.1.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A0F OCA].  
2A0F is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A0F OCA].  


==Reference==
==Reference==
Structure of the E.coli aspartate transcarbamoylase trapped in the middle of the catalytic cycle., Stieglitz KA, Dusinberre KJ, Cardia JP, Tsuruta H, Kantrowitz ER, J Mol Biol. 2005 Sep 16;352(2):478-86. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16120448 16120448]
Structure of the E.coli aspartate transcarbamoylase trapped in the middle of the catalytic cycle., Stieglitz KA, Dusinberre KJ, Cardia JP, Tsuruta H, Kantrowitz ER, J Mol Biol. 2005 Sep 16;352(2):478-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16120448 16120448]
[[Category: Aspartate carbamoyltransferase]]
[[Category: Aspartate carbamoyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: ZN]]
[[Category: ZN]]
[[Category: allosteric regulation]]
[[Category: allosteric regulation]]
[[Category: alternate conformations]]
[[Category: alternate conformation]]
[[Category: catalytic cycle]]
[[Category: catalytic cycle]]
[[Category: homotropic cooperativity]]
[[Category: homotropic cooperativity]]


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